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Moetsi oa thepa Cilengitide 98% phofo e tšoeu CAS NO.188968-51-6

Cilengitide CAS NO: 188968-51-6
Cilengitide ke peptide ea cyclic pentapeptide e qothisanang lehlokoa le arginine-glycine-aspartate (RGD) peptide sequence.E laola tlamahano ea integrin-ligand.Cilengitide e thibela ka mokhoa o ikhethileng le ka katleho alpha v beta 3 beta le alpha v 5 integrin e kopantsoeng le liprotheine tsa matrix, tse kang Vitronectin, Fibronectin, Fibrinogen, vonWillebrandFactor, Osteopontin, le tse ling.10μMCingiChemicalbooktide e thibela ka botlalo ho khomarela lisele tsa BAE, BME le HUVE ho Vitronectin le Fibronectin.Cilengitide e sebetsa ka har'a lisele tsa BAE tse entsoeng pele ka FGF-2 (kapa VEGF-A) ea collagen ea mahlakore a mararo le mali a fibrin gel ho thibela angiogenesis le IC50 ea 15 le 8μM, le 4 le 3μM, ka ho latellana.Cilengitide e thibela ho ata ha lisele, e etsa hore endothelial cell apoptosis, hape e etsa hore ho be le phapang ea lisele tsa endothelial precursor cell.


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Lebitso la Sehlahiswa Cilengitide
CAS 188968-51-6
foromo ea limolek'hule C27H40N8O7
boima ba molek'hule 588.66
tekano 1.41±0.1 g/cm3(E boletsoeng esale pele)
ho qhibiliha ≥29.43 mg / mL ho DMSO;≥22.56 mg/mL ho H2O
Acidity coefficient (pKa) 4.01±0.10(E boletsoeng esale pele)
lokisa (1)
lokisa (1)
tlhophiso (2)

Boemo ba Khoebo

SaiWanTe (Shanghai) New Material Technology Co.,Ltd .ke setsebi sa R ​​& D le tlhahiso ea likaroloana tsa polasetiki, khoele, li-additives tsa lijo, k'hamphani ea khoebo ea kantle ho naha.Litlolo, joalo-joalo, li na le lifeme tsa tsona, ka hona, re 'nile ra amoheloa e le kannete ke bareki ba bangata.Ha re tobane le likatleho tse ngata hakana, re ntse re ikitlaelletsa ho etsa lintlafatso indastering ena.Sepheo sa rona ke ho hlahisa lihlahisoa tse ntle ka ho fetisisa, ka tšebeletso ea setsebi le boikutlo ba ho etsa hore moreki e mong le e mong a khotsofale.Re labalabela ho sebetsa le uena ho theha likamano tsa win-win le uena.Ka kopo kholiseha hore re tla u fa khotsofalo.

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